Treatment review · GLP-1 · 2026
Tirzepatide
Dual GIP/GLP-1 agonist with strong efficacy for weight and metabolic outcomes.
- Expert score
- 9.3/10
- Community interest (editorial)
- 9.0/10
- Cost per month
- $250–$1500
- Providers offering it
- 26in our directory
Both scores are PeakedLabs editorial assessments — community interest reflects our read of discussion volume and demand, not user ratings.
How it works
“Think of it as turning down hunger signals so eating less feels easier.”
Mechanism of action
Combines GLP-1 and GIP receptor agonism for appetite and metabolic regulation.
Typical dosing
2.5 mg weekly titrated up to 15 mg weekly.
Protocols vary by clinic and individual labs. Dose with a licensed clinician, not a forum thread.
Common use cases
- 01weight loss
- 02metabolic syndrome
- 03insulin resistance
Side effects
- nausea
- diarrhea
- fatigue
Legal & regulatory status
- FDA status
- FDA-approved active ingredient
Prescription only; compounded availability changes with supply/legal status.
Where to get it
Providers below currently advertise relevant glp-1 programs, ranked by PeakedLabs score.
| Provider | Score | Monthly range | Actions |
|---|---|---|---|
| Marek Health | 9.1 | $180–$650 | Visit |
| Defy Medical | 8.9 | $165–$625 | Visit |
| Superpower | 8.9 | $199–$699 | Visit |
| Maximus | 8.8 | $149–$349 | Visit |
| Transcend | 8.5 | $179–$599 | Visit |
| Hims | 8.4 | $39–$399 | Visit |
| Amazing Meds | 8.4 | $185–$620 | Visit |
| TRT Nation | 8.3 | $125–$325 | Visit |
| Peter MD | 8.2 | $129–$399 | Visit |
| HydraMed | 8.2 | $150–$459 | Visit |
| AlynMD | 8.1 | $165–$495 | Visit |
| Ro (Roman) | 8.1 | $30–$450 | Visit |
| Elite HRT | 8.1 | $155–$445 | Visit |
| Viking Alternative | 8.0 | $130–$360 | Visit |
| Evolve Telemed | 8.0 | $159–$430 | Visit |
| GameDay Men's Health | 8.0 | $199–$525 | Visit |
| Aspire Rejuvenation | 8.0 | $165–$499 | Visit |
| Inception Telehealth | 8.0 | $159–$475 | Visit |
| Blokes | 7.9 | $129–$379 | Visit |
| Ola Digital Health | 7.9 | $149–$429 | Visit |
| Frontline Alternative | 7.8 | $145–$425 | Visit |
| Optimal Health | 7.7 | $150–$430 | Visit |
| Matrix Hormones | 7.7 | $149–$430 | Visit |
| Henry Meds | 7.6 | $249–$449 | Visit |
| Shed | 7.4 | $199–$399 | Visit |
| Low T Center | 7.3 | $180–$425 | Visit |
Provider-tracked monthly range: $30–$699
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.
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Frequently asked questions
What is Tirzepatide usually used for?
Tirzepatide is typically discussed for weight loss, metabolic syndrome, insulin resistance. 26 tracked providers currently list options in this category.
How is Tirzepatide commonly dosed?
Common protocols reported by clinics and patients: 2.5 mg weekly titrated up to 15 mg weekly. Always individualize with a licensed clinician.
Is Tirzepatide legal in the U.S.?
Prescription only; compounded availability changes with supply/legal status.
What side effects should I watch for with Tirzepatide?
Commonly reported effects include nausea, diarrhea, fatigue. Escalate any severe or persistent symptoms to your care team quickly.
Treatment Planning
Match Treatment Choice to Provider Execution
Choose providers with reliable monitoring and refill workflows for this treatment category.
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.