The PeakedLabs Journal
Evidence-based guides on performance optimization, hormone therapy, and peptide protocols — written to help you compare before you commit.
GLP-1
10 min
GLP-1 microdosing means using doses below the studied therapeutic range. Here is what the dose-response data implies, why patients try it, and how to vet a provider offering low-dose protocols.
Peptides
9 min
GHK-Cu is a copper peptide with plausible follicular mechanisms and small, mostly older human trials. Here is where it fits relative to proven therapies, and what it cannot replace.
Longevity
10 min
IV NAD+ delivers the highest plasma peaks, oral precursors have the most randomized data, and subcutaneous NAD+ has neither. Here is how to choose without overpaying.
Peptide Education
9 min
TB-500 is a seven-amino-acid fragment of the 43-amino-acid thymosin beta-4 molecule. They are related, not identical — and the label on the vial often blurs the difference.
Men's Health
9 min
Finasteride stops the hormonal driver; minoxidil stimulates regrowth. They solve different problems, which is why combination therapy outperforms either alone.
GLP-1
10 min
Retatrutide microdosing is an experimental dosing approach applied to an experimental drug. Here is how to think about it without confusing anecdote for evidence.
GLP-1
11 min
Retatrutide is not FDA approved. Here is the real regulatory timeline, what the Phase 3 trials showed, and what to use in the meantime instead of buying it from a research vendor.
Peptides
10 min
SS-31 is the most-discussed mitochondrial peptide of 2026. Here is what the mechanism actually supports, what the evidence does not yet show, and how to evaluate access responsibly.
GLP-1
10 min
Orforglipron is a once-daily oral GLP-1 with no food or water timing restrictions. Here is how to evaluate dosing, cost, tolerability, and provider quality before you start.
TRT Safety
10 min
The FDA removed the cardiovascular boxed warning from testosterone products and added blood pressure language. Here is what that actually changes about monitoring, risk, and provider selection.
GLP-1
9 min
CagriSema paired an amylin analogue with semaglutide for ~22-23% weight loss in trials - strong, but it narrowly missed beating tirzepatide. Here is the picture.
Longevity
9 min
Klotho is a naturally declining 'longevity protein' with striking animal data on aging and cognition - but human therapies are only now entering trials.
Peptides
9 min
Compare tesamorelin and CJC-1295 on FDA status, dosing frequency, visceral fat evidence, and side effects so you can choose the right GH peptide pathway.
GLP-1
9 min
Does semaglutide cause hair loss? The real cause is rapid weight loss and nutrition gaps, not the drug itself. Learn the timeline, recovery, and prevention steps.
GLP-1
9 min
What the 2026 trial evidence says about semaglutide and alcohol cravings, the reward-pathway mechanism, limits of the data, and how to discuss it with a provider.
TRT Education
9 min
Is Kyzatrex oral testosterone worth the premium over injections? Learn how it works, effectiveness data, cost trade-offs, the blood-pressure caveat, and best-fit candidates.
Longevity
9 min
What rapamycin actually does for longevity in 2026: the PEARL trial results, low-dose weekly protocols, real risks, monitoring, and choosing a supervised provider.
GLP-1
10 min
GLP-1 agonists can strip muscle along with fat. Learn the strategies — protein targets, resistance training, and peptide adjuncts — that protect lean mass while you lose weight.
Peptide Guides
10 min
Compounding pharmacies now offer both oral and injectable BPC-157. Learn how bioavailability, tissue targeting, and cost differ between the two forms before deciding.
GLP-1
10 min
Compounded semaglutide prescriptions became illegal for most patients after the FDA removed the drug from shortage status. Understand the timeline, what's still available, and how to maintain your treatment.
Peptide Guides
10 min
Peptide stacking can accelerate recovery, body composition, and longevity outcomes — but combining compounds without a framework creates attribution failure and safety risk. This guide covers the protocols that work.
GLP-1
9 min
Compare retatrutide and tirzepatide on efficacy, mechanism, lean-mass effects, availability, and realistic cost so you can choose what fits your situation in 2026.
Peptide Guides
9 min
Compare tesamorelin and sermorelin on potency, FDA status, visceral-fat goals, dosing, and cost so you can match the right GH peptide to your goals in 2026.
Provider Comparisons
9 min
Most online TRT clinics do not bill insurance directly, but HSA/FSA funds, superbills, and insurance-covered labs can cut your real cost. Here is how to compare providers in 2026.
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