PeakedLabs

The PeakedLabs Journal

Research, protocols, and provider comparisons

Evidence-based guides on performance optimization, hormone therapy, and peptide protocols — written to help you compare before you commit.

Provider Comparisons

5 min

Best Online TRT Clinics With Insurance Options (2026)

Most online TRT clinics do not bill insurance directly, but HSA/FSA funds, superbills, and insurance-covered labs can cut your real cost. Here is how to compare providers in 2026.

Peptides

15 min

Ipamorelin Dosage and Protocol Guide: Injection, Timing, and Cycle (2026)

Ipamorelin is typically dosed at 200–300 mcg per injection, administered subcutaneously at bedtime (fasted) to maximize growth hormone pulse amplitude. This protocol guide covers standard dose ranges, injection technique, timing, cycle structure, stacking with CJC-1295, and what labs to monitor.

Peptides

16 min

Sermorelin Dosage and Protocol Guide: Injection, Timing, and Cycle (2026)

Sermorelin is typically dosed at 0.2–0.3 mg (200–300 mcg) per injection, administered subcutaneously at bedtime to align with the body's natural growth hormone pulse. This protocol guide covers standard dose ranges, injection technique, timing rationale, cycle structure, stacking with ipamorelin or CJC-1295, and what labs to monitor.

TRT & Health

16 min

Testosterone and Type 2 Diabetes: What the Evidence Shows (2026 Guide)

Low testosterone and type 2 diabetes co-occur in 25–40% of men with T2DM. TRT consistently improves HbA1c, fasting glucose, and insulin sensitivity in hypogonadal diabetic men across multiple RCTs — including Hackett et al. (2016) showing −0.4% HbA1c vs placebo. Here is what the evidence shows.

Peptides

17 min

CJC-1295 + Ipamorelin Stack: Protocol, Dosing, Results, and What to Expect (2026 Guide)

The CJC-1295 + Ipamorelin stack is the most commonly prescribed growth hormone peptide combination in telehealth clinics. By combining a GHRH analog (CJC-1295) with a ghrelin receptor agonist (Ipamorelin), the stack stimulates GH release through two complementary pathways — producing a synergistic pulse that exceeds either peptide alone. Here is what the evidence and clinical experience show about protocols, dosing, results, and realistic expectations.

Peptides

16 min

TB-500 Dosage and Protocol Guide: Injection, Timing, and Cycle (2026)

TB-500 dosing uses a two-phase approach: a loading period at higher doses followed by a lower maintenance phase. This protocol guide covers standard dosing ranges, injection technique, cycle structure, stacking strategies, and what clinical monitoring responsible prescribers require.

TRT & Health

18 min

Testosterone and Inflammation: What the Evidence Shows (2026 Guide)

Low testosterone and chronic inflammation are closely linked — and the relationship runs in both directions. Low T elevates CRP, IL-6, TNF-α, and other inflammatory markers. Chronic inflammation suppresses testosterone production. TRT, when used appropriately, consistently reduces inflammatory burden. Here is the full evidence base.

Peptides & Compounds

16 min

5-Amino-1MQ: What the Evidence Shows for Fat Loss and NAD+ Metabolism (2026 Guide)

5-Amino-1MQ is an NNMT inhibitor with compelling fat loss and metabolic data in animal models. It works by increasing intracellular NAD+ levels in adipose tissue and reactivating metabolically dormant fat cells. Human data is limited — but for men interested in metabolic optimization, here is the full evidence picture.

TRT & Health

15 min

Testosterone and Metabolic Syndrome: What the Evidence Shows (2026 Guide)

Low testosterone and metabolic syndrome are deeply intertwined — each worsens the other. Up to 40% of men with metabolic syndrome have clinically low testosterone. TRT consistently improves insulin sensitivity, waist circumference, triglycerides, and blood pressure in hypogonadal men. Here is what the evidence shows.

Peptides

16 min

Cerebrolysin Peptide: What the Evidence Shows for Cognitive Function and Neuroprotection (2026 Guide)

Cerebrolysin is a porcine brain-derived peptide preparation containing low-molecular-weight neuropeptides and free amino acids that mimic the activity of endogenous neurotrophic factors. It is one of the most clinically studied neuropeptides in the world — with 200+ clinical trials spanning stroke, traumatic brain injury, Alzheimer's disease, and vascular dementia. Here is what the evidence actually shows.

Peptides

19 min

Humanin Peptide: What the Evidence Shows for Neuroprotection and Longevity (2026 Guide)

Humanin was discovered inside the mitochondrial genome of an Alzheimer's patient who never developed the disease. Since then, it's emerged as one of the most powerful neuroprotective peptides known — protecting neurons from amyloid-beta toxicity, lowering IGF-1, reducing inflammatory cytokines, and extending lifespan in animal models. In 2026, it's a cornerstone of serious longevity protocols.

Peptides

18 min

Tesamorelin Peptide: What the Evidence Shows for GH, Fat Loss, and Cognition (2026 Guide)

Tesamorelin is the only peptide in the growth hormone-releasing hormone (GHRH) class with full FDA approval — cleared for visceral fat reduction in HIV-associated lipodystrophy. That FDA approval means it has more robust clinical trial data behind it than virtually any other GH peptide. In 2026, it's one of the most evidence-backed tools in performance medicine for visceral fat loss, body composition, and emerging cognitive applications.

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