Treatment review · GLP-1 · 2026
Retatrutide
Triple agonist (GLP-1/GIP/glucagon) in late-stage development for obesity treatment.
- Expert score
- 8.8/10
- Community interest (editorial)
- 8.1/10
- Cost per month
- $300–$900
- Providers offering it
- 25in our directory
Both scores are PeakedLabs editorial assessments — community interest reflects our read of discussion volume and demand, not user ratings.
How it works
“Think of it as turning down hunger signals so eating less feels easier.”
Mechanism of action
Targets multiple incretin and glucagon pathways to drive appetite and energy-balance changes.
Typical dosing
Investigational protocols vary; clinical titration frameworks still evolving.
Protocols vary by clinic and individual labs. Dose with a licensed clinician, not a forum thread.
Common use cases
- 01advanced weight loss
- 02metabolic optimization
Side effects
- nausea
- GI upset
- increased heart rate
Legal & regulatory status
- FDA status
- Investigational
Investigational; not broadly approved for routine prescribing.
Where to get it
Providers below currently advertise relevant glp-1 programs, ranked by PeakedLabs score.
| Provider | Score | Price | Actions |
|---|---|---|---|
| Marek Health | 9.1 | $180–$650/mo | Visit |
| Defy Medical | 8.9 | $165–$625/mo | Visit |
| Superpower | 8.9 | $349/year | Visit |
| Maximus | 8.8 | $149–$349/mo | Visit |
| Transcend | 8.5 | $179–$599/mo | Visit |
| Hims | 8.4 | $39–$399/mo | Visit |
| Amazing Meds | 8.4 | $185–$620/mo | Visit |
| TRT Nation | 8.3 | $125–$325/mo | Visit |
| Peter MD | 8.2 | $129–$399/mo | Visit |
| HydraMed | 8.2 | $150–$459/mo | Visit |
| AlynMD | 8.1 | $165–$495/mo | Visit |
| Ro (Roman) | 8.1 | $30–$450/mo | Visit |
| Elite HRT | 8.1 | $155–$445/mo | Visit |
| Viking Alternative | 8.0 | $130–$360/mo | Visit |
| Evolve Telemed | 8.0 | $159–$430/mo | Visit |
| GameDay Men's Health | 8.0 | $199–$525/mo (est.) | Visit |
| Aspire Rejuvenation | 8.0 | $165–$499/mo | Visit |
| Inception Telehealth | 8.0 | $159–$475/mo | Visit |
| Blokes | 7.9 | $129–$379/mo | Visit |
| Frontline Alternative | 7.8 | $145–$425/mo | Visit |
| Optimal Health | 7.7 | $150–$430/mo | Visit |
| Matrix Hormones | 7.7 | $149–$430/mo | Visit |
| Henry Meds | 7.6 | $249–$449/mo | Visit |
| Shed | 7.4 | $199–$399/mo | Visit |
| Low T Center | 7.3 | $180–$425/mo | Visit |
Provider-tracked monthly range: $30–$650
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.
Experts covering this treatment
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Frequently asked questions
What is Retatrutide usually used for?
Retatrutide is typically discussed for advanced weight loss, metabolic optimization. 25 tracked providers currently list options in this category.
How is Retatrutide commonly dosed?
Common protocols reported by clinics and patients: Investigational protocols vary; clinical titration frameworks still evolving. Always individualize with a licensed clinician.
Is Retatrutide legal in the U.S.?
Investigational; not broadly approved for routine prescribing.
What side effects should I watch for with Retatrutide?
Commonly reported effects include nausea, GI upset, increased heart rate. Escalate any severe or persistent symptoms to your care team quickly.
Treatment Planning
Match Treatment Choice to Provider Execution
Choose providers with reliable monitoring and refill workflows for this treatment category.
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.