Treatment review · Hormone · 2026
Pregnenolone
Neurosteroid precursor used in hormone optimization and cognitive support stacks.
- Editorial score
- 6.8/10
- Community interest (editorial)
- 7.0/10
- Estimated cost per month
- $12–$60
- Providers with related programs
- 29in our directory
Both scores are PeakedLabs editorial assessments — community interest reflects our read of discussion volume and demand, not user ratings. Cost ranges are editorial estimates, not quotes or purchasable offers. A related program does not confirm that a clinic offers this specific treatment or that it is appropriate for you.
How it works
“Think of it as restoring key body messengers when levels are too low or out of balance.”
Mechanism of action
Acts as a precursor for progesterone, DHEA, and downstream steroid hormones.
Typical dosing
10-100 mg orally daily based on labs and symptoms.
Protocols vary by clinic and individual labs. Dose with a licensed clinician, not a forum thread.
Common use cases
- 01hormone balance
- 02mood
- 03cognitive support
Side effects
- irritability
- acne
- sleep disruption
Legal & regulatory status
- FDA status
- Supplement/compounded depending on route
Available as supplement or prescription-strength compounded form.
Provider research
Providers below advertise related hormone programs, ranked by PeakedLabs editorial score. Confirm the specific treatment, current availability and full price directly.
| Provider | Score | Price | Actions |
|---|---|---|---|
| Marek Health | 9.1 | $180–$650/mo | Visit |
| Defy Medical | 8.9 | $165–$625/mo | Visit |
| Superpower | 8.9 | $199/year | Visit |
| Maximus | 8.8 | $149–$349/mo | Visit |
| Transcend | 8.5 | $179–$599/mo | Visit |
| Hims | 8.4 | All-in monthly total not verified | Visit |
| Amazing Meds | 8.4 | $185–$620/mo | Visit |
| TRT Nation | 8.3 | $125–$325/mo | Visit |
| Peter MD | 8.2 | $129–$399/mo | Visit |
| HydraMed | 8.2 | $150–$459/mo | Visit |
| AlynMD | 8.1 | $165–$495/mo | Visit |
| Elite HRT | 8.1 | $155–$445/mo | Visit |
| Viking Alternative | 8.0 | $130–$360/mo | Visit |
| Evolve Telemed | 8.0 | $159–$430/mo | Visit |
| GameDay Men's Health | 8.0 | $199–$525/mo (est.) | Visit |
| Aspire Rejuvenation | 8.0 | $165–$499/mo | Visit |
| Inception Telehealth | 8.0 | $159–$475/mo | Visit |
| Blokes | 7.9 | $129–$379/mo | Visit |
| Alpha Hormones | 7.9 | $140–$415/mo | Visit |
| Fountain TRT | 7.8 | $145–$220/mo | Visit |
| Prime Body | 7.8 | $149–$435/mo | Visit |
| Frontline Alternative | 7.8 | $145–$425/mo | Visit |
| Optimal Health | 7.7 | $150–$430/mo | Visit |
| Matrix Hormones | 7.7 | $149–$430/mo | Visit |
| TRT.md | 7.6 | $139–$245/mo | Visit |
| Total Care Medical | 7.5 | $155–$475/mo | Visit |
| Royal Medical Center | 7.5 | $195–$300/mo | Visit |
| Rugiet | 7.4 | $45–$299/mo | Visit |
| Low T Center | 7.3 | $180–$425/mo | Visit |
Related-program monthly range (may include estimates, not a treatment quote): $45–$650
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.
Experts covering this treatment
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Related treatments
Frequently asked questions
What is Pregnenolone usually used for?
Pregnenolone is typically discussed for hormone balance, mood, cognitive support. 29 tracked providers currently list options in this category.
How is Pregnenolone commonly dosed?
Common protocols reported by clinics and patients: 10-100 mg orally daily based on labs and symptoms. Always individualize with a licensed clinician.
Is Pregnenolone legal in the U.S.?
Available as supplement or prescription-strength compounded form.
What side effects should I watch for with Pregnenolone?
Commonly reported effects include irritability, acne, sleep disruption. Escalate any severe or persistent symptoms to your care team quickly.
Treatment Planning
Match Treatment Choice to Provider Execution
Choose providers with reliable monitoring and refill workflows for this treatment category.
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.