Treatment review · Peptide · 2026
TB-500 (Thymosin Beta-4 Fragment)
Peptide fragment used in recovery protocols for soft tissue healing support.
- Expert score
- 7.7/10
- Community interest (editorial)
- 8.4/10
- Cost per vial
- $110–$280
- Providers offering it
- 4in our directory
Both scores are PeakedLabs editorial assessments — community interest reflects our read of discussion volume and demand, not user ratings.
How it works
“Think of it as sending a targeted text message to specific cells to speed up repair or signaling.”
Mechanism of action
May promote cell migration and tissue remodeling through actin regulation.
Typical dosing
2-5 mg weekly for 4-6 weeks, then lower maintenance protocols.
Protocols vary by clinic and individual labs. Dose with a licensed clinician, not a forum thread.
Common use cases
- 01muscle recovery
- 02tendon healing
- 03inflammation management
Side effects
- fatigue
- water retention
- headache
Legal & regulatory status
- FDA status
- Compounding category dependent
Generally offered via compounding channels when allowed.
Post-February 2026 update: many injectable peptides are now subject to tighter compounding enforcement, so pharmacy and state compliance checks are essential before starting treatment.
Where to get it
Providers below currently advertise relevant peptide programs, ranked by PeakedLabs score.
| Provider | Score | Monthly range | Actions |
|---|---|---|---|
| Defy Medical | 8.9 | $165–$625 | Visit |
| HydraMed | 8.2 | $150–$459 | Visit |
| Elite HRT | 8.1 | $155–$445 | Visit |
| Viking Alternative | 8.0 | $130–$360 | Visit |
Provider-tracked monthly range: $130–$625
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.
Experts covering this treatment
Expert directoryThe PeakedLabs guide · $29, one-time
The Complete Peptide Therapy Guide
36 pages on BPC-157, TB-500, CJC-1295/Ipamorelin, and more: dosing frameworks, baseline lab checklists, side-effect stop rules, and monthly cost math—the homework before you pay any clinic.
Related treatments
Frequently asked questions
What is TB-500 (Thymosin Beta-4 Fragment) usually used for?
TB-500 (Thymosin Beta-4 Fragment) is typically discussed for muscle recovery, tendon healing, inflammation management. 4 tracked providers currently list options in this category.
How is TB-500 (Thymosin Beta-4 Fragment) commonly dosed?
Common protocols reported by clinics and patients: 2-5 mg weekly for 4-6 weeks, then lower maintenance protocols. Always individualize with a licensed clinician.
Is TB-500 (Thymosin Beta-4 Fragment) legal in the U.S.?
Generally offered via compounding channels when allowed. Post-February 2026 update: many injectable peptides are now subject to tighter compounding enforcement, so pharmacy and state compliance checks are essential before starting treatment.
What side effects should I watch for with TB-500 (Thymosin Beta-4 Fragment)?
Commonly reported effects include fatigue, water retention, headache. Escalate any severe or persistent symptoms to your care team quickly.
Treatment Planning
Match Treatment Choice to Provider Execution
Choose providers with reliable monitoring and refill workflows for this treatment category.
Disclosure: PeakedLabs may earn a commission from partner links. Editorial scoring and rankings remain independent.